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Tumor Necrosis Factor alpha (TNF alpha) (N-Term) Peptid

TNF alpha Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511929
  • Target Alle TNF alpha Produkte
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    STESMIRDVE LAEEALPKKT GGPQGSRRCL FLSLFSFLIV AGATTLFCLL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- TNF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Synonyme
    DIF Peptide, TNF-alpha Peptide, TNFA Peptide, TNFSF2 Peptide, RATTNF Peptide, Tnfa Peptide, tnf Peptide, TNF-a Peptide, TNFalpha Peptide, Tnfsf1a Peptide, TNFa Peptide, cTNF Peptide, Tnf-alpha Peptide, tnfa-like Peptide, TNF-ALPHA Peptide, dif Peptide, tnfa Peptide, xtnf Peptide, tnfsf2 Peptide, tnf-alpha Peptide, Cachectin Peptide, tumor necrosis factor Peptide, tumor necrosis factor b (TNF superfamily, member 2) Peptide, tumor necrosis factor alpha Peptide, tumor necrosis factor a (TNF superfamily, member 2) Peptide, TNF Peptide, Tnf Peptide, tnf Peptide, tnfb Peptide, tnf-alpha Peptide, LOC103694380 Peptide, tnfa Peptide
    Hintergrund
    This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

    Alias Symbols: DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha

    Protein Size: 233
    Gen-ID
    7124
    NCBI Accession
    NM_000594, NP_000585
    UniProt
    P01375
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