This is a synthetic peptide designed for use in combination with anti-KCNB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
Kv2.1/KCNB1 (KCNB1)
(Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))
Synonyme
KCNB1 Peptide, Kcnb1 Peptide, Kcr1-1 Peptide, Kv2.1 Peptide, Shab Peptide, DRK1PC Peptide, DRK1 Peptide, KV2.1 Peptide, h-DRK1 Peptide, potassium voltage-gated channel subfamily B member 1 Peptide, potassium voltage-gated channel, Shab-related subfamily, member 1 Peptide, potassium channel, voltage gated Shab related subfamily B, member 1 Peptide, potassium voltage gated channel, Shab-related subfamily, member 1 Peptide, KCNB1 Peptide, kcnb1 Peptide, LOC100541632 Peptide, Kcnb1 Peptide
Hintergrund
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.