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Vascular Endothelial Growth Factor A (VEGFA) (C-Term) Peptid

VEGFA Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511623
  • Target Alle VEGFA Produkte
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    ECRPKKDRAR QEKKSVRGKG KGQKRKRKKS RYKSWSVYVG ARCCLMPWSL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-VEGFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Synonyme
    MVCD1 Peptide, VEGF Peptide, VPF Peptide, Vegf Peptide, Vegf120 Peptide, Vegf164 Peptide, Vegf188 Peptide, Vpf Peptide, vegf Peptide, vegfa Peptide, wu:fj82c06 Peptide, VEGF-A Peptide, VEGF164 Peptide, eVEGF120 Peptide, eVEGF164 Peptide, vegf-a Peptide, vpf Peptide, vefg Peptide, si:dkey-14d8.3 Peptide, wu:fd42e02 Peptide, vascular endothelial growth factor A Peptide, vascular endothelial growth factor Aa Peptide, vascular endothelial growth factor A L homeolog Peptide, vascular endothelial growth factor Ab Peptide, VEGFA Peptide, Vegfa Peptide, vegfaa Peptide, vegfa.L Peptide, vegfa Peptide, vegfab Peptide
    Hintergrund
    This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

    Alias Symbols: Name=VEGFA,

    Protein Size: 327
    Gen-ID
    7422
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