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Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) (N-Term) Peptid

CYP2E1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511233
  • Target Alle CYP2E1 Produkte
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PAFHAHRDRG IIFNNGPTWK DIRRFSLTTL RNYGMGKQGN ESRIQREAHF
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CP2E1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Synonyme
    CYP2E1 Peptide, CYP2E Peptide, CYPIIE1 Peptide, CPE1 Peptide, P450-J Peptide, P450C2E Peptide, Cyp2e Peptide, cytochrome P450, family 2, subfamily E, polypeptide 1 Peptide, cytochrome P450 2E1 Peptide, cytochrome P450 2E1-like Peptide, cytochrome P450 family 2 subfamily E member 1 Peptide, cytochrome P450, family 2, subfamily e, polypeptide 1 Peptide, CYP2E1 Peptide, PTRG_07411 Peptide, LOC100342572 Peptide, LOC100727914 Peptide, LOC101843716 Peptide, Cyp2e1 Peptide
    Hintergrund
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

    Alias Symbols: CYP2E1,CYP2E,

    Protein Size: 493
    Gen-ID
    1571
    NCBI Accession
    NP_000764
    UniProt
    P05181
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