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CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (Middle Region) Peptid

CRADD Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511035
  • Target Alle CRADD Produkte
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PAGDRLTGIP SHILNSSPSD RQINQLAQRL GPEWEPMVLS LGLSQTDIYR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CRADD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Synonyme
    cradd Peptide, MGC89035 Peptide, zgc:101717 Peptide, CRADD Peptide, DKFZp468A2219 Peptide, LOC100226369 Peptide, raidd Peptide, MGC78788 Peptide, MRT34 Peptide, RAIDD Peptide, CASP2 and RIPK1 domain containing adaptor with death domain Peptide, CASP2 and RIPK1 domain containing adaptor with death, gene 1 Peptide, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog Peptide, CRADD Peptide, cradd.1 Peptide, cradd Peptide, cradd.2.S Peptide, Cradd Peptide
    Hintergrund
    The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.

    Alias Symbols: CRADD, RAIDD,

    Protein Size: 199
    Gen-ID
    8738
    NCBI Accession
    NP_003796
    UniProt
    P78560
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