Caspase Recruitment Domain Family, Member 8 (CARD8) (N-Term) Peptid
CARD8
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CARD8 Produkte
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
- Protein Region
- N-Term
- Spezies
- Human
- Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CARD8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
- Synonyme
- CARD8 Peptide, CARDINAL Peptide, DACAR Peptide, DAKAR Peptide, NDPP Peptide, NDPP1 Peptide, TUCAN Peptide, caspase recruitment domain family, member 8 Peptide, caspase recruitment domain-containing protein 8 Peptide, caspase recruitment domain family member 8 Peptide, CARD8 Peptide, LOC718594 Peptide
- Hintergrund
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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Protein Size: 286 - Gen-ID
- 22900
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