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Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 1-27) Peptid

ADCYAP1
Produktnummer ABIN399691
  • Target Alle PACAP (ADCYAP1) Produkte
    PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))
    Protein Region
    AA 1-27
    Aufreinigung
    Purified
    Reinheit
    > 95 %
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    -20 °C
  • Target
    PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))
    Synonyme
    PACAP Peptide, grf Peptide, Pacap Peptide, adcyap1 Peptide, GRF-PACAP Peptide, zgc:103760 Peptide, xx:af217251 Peptide, pacap Peptide, ADCYAP1 Peptide, PACAP2 Peptide, acap1l Peptide, pacap1b Peptide, wu:fj30e08 Peptide, zgc:101522 Peptide, zgc:92555 Peptide, adenylate cyclase activating polypeptide 1 Peptide, adenylate cyclase activating polypeptide 1a Peptide, adenylate cyclase activating polypeptide 1 (pituitary) Peptide, adenylate cyclase activating polypeptide 1b Peptide, ADCYAP1 Peptide, Adcyap1 Peptide, adcyap1a Peptide, adcyap1 Peptide, adcyap1b Peptide
    Hintergrund
    PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. PACAP (1-27) shows considerable homology with Vasoactive Intestinal Polypeptide (VIP), and can stimulate adenylate cyclase much more potently than VIP. The PACAP(1-27)-induced increase in pancreatic venous blood flow was blocked by PACAP(6-27) but not by atropine. Therefore, the endocrine secretagogue effect of PACAP(1-27) is primarily mediated by the PAC(1) receptor, and that PACAP(1-27) may interact with muscarinic receptor function in PACAP-induced insulin and glucagon secretion in the canine pancreas in vivo.
    CAS-Nummer
    127317-03-7
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