Shil, Kwon, Zhu, Verma, Daniell, Li: "Oral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental uveitis and autoimmune uveoretinitis." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 12, pp. 2069-82, (2014) (PubMed).
Target
RBP3
(Retinol Binding Protein 3, Interstitial (RBP3))
This peptide consisting of residues 1-20 of human interphotoreceptor retinoid binding protein peptide (IRBP) has been shown to induce posterior uveitis (EAU) in several studies. Experimental autoimmune uveitis is an animal model for endogenous human posterior uveitis.