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Paternally Expressed 10 (PEG10) (N-Term) Peptid

PEG10 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN2184261
  • Target Alle PEG10 Produkte
    PEG10 (Paternally Expressed 10 (PEG10))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    SMMTGRAARW ASAKLERSHY LMHNYPAFMM EMKHVFEDPQ RREVAKRKIR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PEG10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PEG10 (Paternally Expressed 10 (PEG10))
    Synonyme
    EDR Peptide, HB-1 Peptide, MEF3L Peptide, Mar2 Peptide, Mart2 Peptide, RGAG3 Peptide, AA407948 Peptide, Edr Peptide, MyEF-3 Peptide, paternally expressed 10 Peptide, PEG10 Peptide, Peg10 Peptide
    Hintergrund
    This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.

    Alias Symbols: EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3

    Protein Size: 708
    Molekulargewicht
    80 kDa
    Gen-ID
    23089
    NCBI Accession
    NM_015068, NP_055883
    UniProt
    Q86TG7
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