Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (C-Term) Peptid
TCF7
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle TCF7 Produkte
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- AKYYELARKE RQLHMQLYPG WSARDNYGKK KRRSREKHQE STTDNSLHYS
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TCF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
- Synonyme
- TCF-1 Peptide, AI465550 Peptide, Tcf1 Peptide, Xtcf-1 Peptide, Xtcf1 Peptide, tcf-1 Peptide, tcf1 Peptide, tcf7 Peptide, transcription factor 7 Peptide, transcription factor 7, T cell specific Peptide, transcription factor 7 S homeolog Peptide, TCF7 Peptide, Tcf7 Peptide, tcf7 Peptide, tcf7.S Peptide
- Hintergrund
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The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TCF-1
Protein Size: 365 - Molekulargewicht
- 40 kDa
- Gen-ID
- 6932
- NCBI Accession
- NM_213648, NP_998813
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