anti-Hund Manic Fringe Antikörper für Western Blotting

Recommended Manic Fringe Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
MFNG Antikörper
  • AW546563
  • MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • MFNG
  • Mfng
Epitop
Middle Region
5
5
4
4
4
2
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
56
30
30
5
5
5
4
4
3
2
2
2
1
1
Wirt
Kaninchen
47
10
2
1
Klonalität
Polyklonal
Konjugat
Dieser Manic Fringe Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
45
18
13
9
7
4
3
3
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2783425
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
2.9137778 ABIN2783426 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
2.9137778 ABIN2782201 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN799234 WB Rabbit AA 241-290 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1913324 IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1913322 IHC IHC (p) WB Rabbit IgG AA 211-260 Anmelden zum Anzeigen Polyclonal 0

General

Antigen MFNG Antikörper
Epitop Middle Region
(5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(56), (30), (30), (5), (5), (5), (4), (4), (3), (2), (2), (2), (1), (1)
Wirt Kaninchen
(47), (10), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser Manic Fringe Antikörper ist unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(45), (18), (13), (9), (7), (4), (3), (3), (1)
Pubmed 1 Publikation vorhanden
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Produktdetails anti-Manic Fringe Antikörper

Target Details Manic Fringe Anwendungsinformationen Handhabung Referenzen für anti-Manic Fringe Antikörper (ABIN2783425) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN980025.
Sequenz MAPWASGSRF MDTSALIRLP DDCTMGYIIE CKLGGRLQPS PLFHSHLETL
Homologie Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against MFNG. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MFNG
Plasmids, Primers & others

Target Details Manic Fringe

Produktdetails anti-Manic Fringe Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Manic Fringe Antikörper (ABIN2783425) Bilder zurück nach oben
Antigen
Andere Bezeichnung MFNG (MFNG Antibody Abstract)
Hintergrund MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: DLL1, JAG1, NOTCH2, NOTCH1,
Protein Size: 321
Molekulargewicht 36 kDa
Gen-ID 4242
NCBI Accession NM_002405, NP_002396
UniProt O00587
Pathways Notch Signalweg

Anwendungsinformationen

Produktdetails anti-Manic Fringe Antikörper Target Details Manic Fringe Handhabung Referenzen für anti-Manic Fringe Antikörper (ABIN2783425) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 321 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Manic Fringe Antikörper Target Details Manic Fringe Anwendungsinformationen Referenzen für anti-Manic Fringe Antikörper (ABIN2783425) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Manic Fringe Antikörper (ABIN2783425)

Produktdetails anti-Manic Fringe Antikörper Target Details Manic Fringe Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Veeraraghavalu, Pett, Kumar, Nair, Rangarajan, Stanley, Krishna: "Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation." in: Journal of virology, Vol. 78, Issue 16, pp. 8687-700, 2004

Bilder

Produktdetails anti-Manic Fringe Antikörper Target Details Manic Fringe Anwendungsinformationen Handhabung Referenzen für anti-Manic Fringe Antikörper (ABIN2783425) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-MFNG (MFNG) (Middle Region) antibody (ABIN2783425) WB Suggested Anti-MFNG Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...