Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Study utilizing integrative analysis of transcriptomic, metabolomic, and clinical data propose a model of GOT2 transcriptional regulation, in which the cooperative phosphorylation of STAT3 and direct joint binding of STAT3 and p65/NF-kappaB to the proximal GOT2 promoter are important. Furthermore, high aberrant GOT2 expression is prognostic in diffuse large B-cell lymphoma.
The results of our study on this larger than 5800-patient cohort suggest beneficial effects of high B12 vitamin level, negative effects of high sodium levels or high AST (aspartate aminotransferase) liver enzyme levels to cognition.
Like in adults, FABP seems to be associated with markers of metabolic risk in obese adolescents
Data suggest that, in context of abnormal hepatic lipid accumulation in nonalcoholic fatty liver disease, circulating GOT2 rises due to up-regulation of hepatic expression of GOT2 associated with greater gluconeogenesis and insulin resistance.
A previously unknown mechanism by which GOT2 acetylation stimulates the malate-aspartate NADH shuttle activity and oxidative protection.
High glucose infusion was associated with increased expression of higher plasma membrane-associated fatty acid-binding protein (FABPpm).
The lipid binding process in L-FABP is associated with backbone dynamics.
Frequency of polymorphism are similar in control groups and schizophrenics.
PTLP activity is positively associated with serum ALT1, GOT1 and GOT2 in type 2 diabetes mellitus and metabolic syndrome.
Thermal aggregation of aspartate aminotransferase from pig heart mitochondria (mAAT) has been studied at various temperatures and various protein concentrations by dynamic light scattering.
GOT2-mediated ATP synthesis may be a pivotal mechanism underlying the protective effect of febuxostat against neurodegeneration in EA
it is quite likely that the down regulation of GOT2 after blast exposure is playing a significant role in mitochondrial dysfunction after blast exposure
The role of mAspAT in vivo is to control the levels of endogenous kynurenic acid (KYNA) through modulation of the mAspAt in the mouse brain.
KAT IV inhibited by equimolar tryptophan and aspartate, and half-life is 6.5 minutes at 65 degree C.
FAT/CD36 and FABPpm protein content was increased in red muscles in IL-6(-/-) mice compared to WT mice at 4 (RG) and 12 months (soleus and RG).
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
, aspartate aminotransferase 2
, aspartate aminotransferase, mitochondrial
, aspartate transaminase 2
, fatty acid-binding protein
, glutamate oxaloacetate transaminase 2
, glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
, kynurenine aminotransferase 4
, kynurenine aminotransferase IV
, kynurenine--oxoglutarate transaminase 4
, kynurenine--oxoglutarate transaminase IV
, plasma membrane-associated fatty acid-binding protein
, transaminase A
, mitochondrial aspartate aminotransferase
, plasma membrane fatty acid binding protein
, Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2)
, aspartate aminotransferase 2a
, glutamate oxaloacetate transaminase 2, mitochondrial