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anti-Human MTR Antikörper:
anti-Mouse (Murine) MTR Antikörper:
anti-Rat (Rattus) MTR Antikörper:
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Human Polyclonal MTR Primary Antibody für ELISA, IHC - ABIN256634
Jiang, Hurt, Breen, Stabler, Allen, Orlicky, Maclean: Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. in Biology open 2015
Show all 2 Pubmed References
Genotypes of transcobalamin 2 (TCN2 (zeige TCN2 Antikörper)) rs1801198, methionine synthase (MTR) rs1805087, methionine synthase reductase (MTRR (zeige MTRR Antikörper)) rs1801394, and methylene tetrahydrofolate reductase (MTHFR (zeige MTHFR Antikörper)) rs1801133 were examined in 201 children with Autism Spectrum Disorder and 200 healthy controls from the Han Chinese population. Our results showed no association of all examined SNPs with childhood ASD (zeige ARSD Antikörper) and its severity.
Methylene tetrahydrofolate reductase (MTHFR (zeige MTHFR Antikörper)) C677T, 5-methyltetrahydrofolate homocysteine methyltransferase (MTR) A2756G and 5- methyltetrahydrofolate homocysteine methyltransferase reductase (MTRR (zeige MTRR Antikörper)) A66G were shown to be positively associatiated with homocysteine, while nonvegetarian diet, serine hydroxymethyltransferase 1 (SHMT1 (zeige SHMT1 Antikörper)) C1420T and TYMS (zeige TYMS Antikörper) 5'-UTR (zeige UTS2R Antikörper) 28 bp tandem repeat exhibited negative association with homocysteine.
GG homozygous and G alleles of methionine synthase A2756G polymorphism were not associated with risks of non-Hodgkin lymphoma (NHL (zeige RTEL1 Antikörper)), Hodgkin lymphoma (HL), the subtype of NHL (zeige RTEL1 Antikörper) including the diffuse large B-cell lymphoma and follicular lymphoma.
SNPs in folate pathway genes MTHFR (zeige MTHFR Antikörper)/ MTR/ACE (zeige ACE Antikörper) and hyperhomocysteinemia have roles in risk of coronary artery disease.
Data indicate that two noncoding 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) variants, rs28372871 and rs1131450 were independently associated with a significantly increased risk of prostate cancer (PCa (zeige FLVCR1 Antikörper)).
Based on the results, an MTRA2756G polymorphism which changes activity and stability of the methionine synthase associated with prostate cancer in men.
MTR CpG sites were hypermethylated in preterm placenta. Methylated CpG sites were negatively associated with maternal plasma vitamin B12 (zeige NDUFB3 Antikörper) levels.
tagSNPs in MTHFR (zeige MTHFR Antikörper), MTR, MTRR (zeige MTRR Antikörper), and TCN2 (zeige TCN2 Antikörper) were not associated with NSCLP in our study, but continued exploration, including allele frequency of various populations and molecular mechanism of the gene-gene interactions of the genes, may provide additional insight into NSCLP.
MTHFR (zeige MTHFR Antikörper) A1298C and MS A2756G polymorphisms may be unrelated to male infertility.
The evaluation of genetic association showed that, MTHFR (zeige MTHFR Antikörper) C6877T (OR: 8.89, 95% CI: 2.01-39.40) and MTR A2756G (OR: 1.48, 95% CI: 1.09-2.00) polymorphisms associated with higher risk of CVD.
These findings indicate that greater synthesis of phosphatidylcholine (zeige SGMS1 Antikörper) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.
5-methyltetrahydrofolate-homocysteine methyltransferase 1
, cobalamin-dependent methionine synthase
, methionine synthase
, vitamin-B12 dependent methionine synthase
, 5-methyltetrahydrofolate--homocysteine methyltransferase