CMV IgA ELISA is intended for use in the detection of IgA antibodies to Cytomegalovirus (CMV) infection.
Proben
Serum
Analytische Methode
Qualitative
Spezifität
97.20 %
Sensitivität
99.20%
Applikationshinweise
Optimal dilution should be determined by the end user.
Probenmenge
5 μL
Testdauer
1 - 2 h
Plattentyp
Pre-coated
Beschränkungen
Nur für Forschungszwecke einsetzbar
Lagerung
4 °C
Haltbarkeit
12-18 months
Target
IgA (CMV IgA)
Substanzklasse
Viral Protein
Hintergrund
Cytomegalovirus is a herpes virus and a leading biological factor causing congenital abnormalities and complications among those who receive massive blood transfusions and immunosuppressive therapy. About half of pregnant women who contract a primary infection spread the disease to their fetus. When acquired in-utero, the infection may cause mental retardation, blindness, and/or deafness. Serological tests for detecting the presence of antibody to CMV can provide valuable information regarding the history of previous infection, diagnosis of active or recent infection, as well as in screening blood for transfusions in newborns and immuno-compromised recipients. The antibodies present to Cytomegalovirus may be of the IgA, IgM and IgG. The physiological function of IgA and its clinical implication is still unclear.