TNFRSF6B ELISA Kit

Produktnummer ABIN6720102

Produktdetails TNFRSF6B ELISA Kit

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 156 pg/mL - 10000 pg/mL

Untere Nachweisgrenze: 156 pg/mL

Applikation: ELISA

Verwendungszweck: Sandwich ELISA for Quantitative Detection of Antigen

Proben: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytische Methode: Quantitative

Produktmerkmale:

Synonyms: DcR3, Decoy Receptor 3, Decoy receptor for Fas ligand, DJ583P15.1.1, M68, M68E, OTTHUMP00000031583, TNF6B_HUMAN, TNFRSF6B, TR6, Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor receptor superfamily member 6b decoy, Tumor necrosis factor receptor superfamily member 6b decoy, UNQ186/PRO212

Background: Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-inducedapoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.

Gene Name: TNFRSF6B

Production: Natural and recombinant human DCR3. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: sf21, Immunogen sequence: V24-H300

Anwendungsinformationen

Applikationshinweise:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human DCR3 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human DCR3 standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 156pg/mL-10000pg/mL

Other Performance Data: DOE: 2-8° C - 02/15/19 -20° C - 08/15/19

Probenmenge: 100 μL

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Details zu TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Andere Bezeichnung: DCR3 - TNFRSF6B (TNFRSF6B Produkte)

Synonyme: DCR3 ELISA Kit, DJ583P15.1.1 ELISA Kit, M68 ELISA Kit, M68E ELISA Kit, TR6 ELISA Kit, dcr3 ELISA Kit, m68 ELISA Kit, tr6 ELISA Kit, TNF receptor superfamily member 6b ELISA Kit, tumor necrosis factor receptor superfamily, member 11b ELISA Kit, regulator of telomere elongation helicase 1 ELISA Kit, TNF receptor superfamily member 6b L homeolog ELISA Kit, TNFRSF6B ELISA Kit, tnfrsf11b ELISA Kit, RTEL1 ELISA Kit, tnfrsf6b ELISA Kit, tnfrsf6b.L ELISA Kit

Gen-ID: 8771

NCBI Accession: NP_003814

UniProt: O95407