CHL1 ELISA Kit

Produktnummer ABIN5510734

Produktdetails CHL1 ELISA Kit

Target: CHL1 (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) (CHL1))

Bindungsspezifität: AA 26-1083

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CHL1/L1CAM-2

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: E26-W1083

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Expressed in the brain, in the cerebellum and in the spinal cord. Detected in the retina and the optic nerve. Expressed in neurons and glial cells in the central nervous system and by Schwann cells in the peripheral nervous system. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu CHL1

Target: CHL1 (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1) (CHL1))

Andere Bezeichnung: Chl1 (CHL1 Produkte)

Synonyme: CALL ELISA Kit, L1CAM2 ELISA Kit, CHL ELISA Kit, CHL1 ELISA Kit, Nrln1 ELISA Kit, VOPT ELISA Kit, A530023M13Rik ELISA Kit, AI465420 ELISA Kit, LICAM2 ELISA Kit, Call ELISA Kit, cell adhesion molecule L1 like ELISA Kit, chordin-like 1 ELISA Kit, cell adhesion molecule L1-like ELISA Kit, CHL1 ELISA Kit, Chrdl1 ELISA Kit, Chl1 ELISA Kit

Hintergrund:

Protein Function: Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane. .

Background: Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the CHL1 gene. This protein is a member of the L1 gene family of neural cell adhesion molecules. By FISH, the CHL1 gene was mapped to chromosome 3p26.1. The protein however has dynamic localisation, meaning that it has not only multiple roles in the cell, but also various locations. This protein may also play a role in the growth of certain cancers.

Synonyms: Neural cell adhesion molecule L1-like protein,Cell adhesion molecule with homology to L1CAM,Chl1-like protein,Close homolog of L1,Processed neural cell adhesion molecule L1-like protein,Chl1,Call,

Full Gene Name: Neural cell adhesion molecule L1-like protein

Cellular Localisation: Cell membrane, Single-pass type I membrane protein. Soluble forms produced by cleavage/shedding also exist.

UniProt: P70232