COL18A1 ELISA Kit
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- Target Alle COL18A1 ELISA Kits anzeigen
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Bindungsspezifität
- AA 1591-1774
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Reaktivität
- Ratte
- Nachweismethode
- Colorimetric
- Methodentyp
- Sandwich ELISA
- Applikation
- ELISA
- Verwendungszweck
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Endostatin
- Marke
- PicoKine™
- Analytische Methode
- Quantitative
- Spezifität
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Expression system for standard: NSO
Immunogen sequence: H1591-K1774 - Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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- Plattentyp
- Pre-coated
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Haltbarkeit
- 12 months
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- Target Alle COL18A1 ELISA Kits anzeigen
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Andere Bezeichnung
- Endostatin (COL18A1 Produkte)
- Synonyme
- KNO ELISA Kit, KNO1 ELISA Kit, KS ELISA Kit, cb371 ELISA Kit, cb529 ELISA Kit, fc96d06 ELISA Kit, sb:cb529 ELISA Kit, wu:fb47h10 ELISA Kit, wu:fb77g12 ELISA Kit, wu:fc50f04 ELISA Kit, wu:fc96d06 ELISA Kit, wu:fk02h12 ELISA Kit, kno ELISA Kit, kno1 ELISA Kit, collagen type XVIII alpha 1 chain ELISA Kit, collagen type XVIII alpha 1 chain a ELISA Kit, collagen, type XVIII, alpha 1 ELISA Kit, collagen type XVIII alpha 1 ELISA Kit, COL18A1 ELISA Kit, col18a1a ELISA Kit, Col18a1 ELISA Kit, col18a1 ELISA Kit
- Substanzklasse
- Chemical
- Hintergrund
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Background: Endostatin is a naturally-occurring 20- kDa C-terminal fragment derived from type XVIII collagen. It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. And It is produced by proteolytic cleavage of collagen XVIII, a member of the multiplexin family that is characterized by interruptions in the triple helix creating multiple domains, by proteases such as cathepsins. Using a genomic clone as a probe for fluorescence in situ hybridization, Endostatin was mapped the COL18A1 gene to 21q22.3. By immunoprecipitation analysis using membrane fractions of human mammary epithelial cells, It showed that endostatin specifically bound to cell surface nucleolin with high affinity. Blockage of nucleolin with neutralizing antibody or knockdown of nucleolin by RNA interference countered the antiendothelial activity of endostatin and abrogated its antiangiogenic and antitumor activity in vivo.
Synonyms: Collagen type XVIII, alpha (I) chain ,Col18a1 ,col18a1 ,
Full Gene Name: collagen, type XVIII, alpha 1
- UniProt
- Q9WUW5
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