TNFSF13 ELISA Kit

Produktnummer ABIN2042703

Produktdetails TNFSF13 ELISA Kit

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 6-10000 pg/mL

Untere Nachweisgrenze: 6 pg/mL

Applikation: ELISA

Marke: BioAssay™

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate pre-coated with anti-TNFSF13/APRIL, Human
Lyophilized recombinant TNFSF13/APRIL, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Human TNFSF13/APRIL in cell culture supernates, serum and plasma (heparin, EDTA).Tumor necrosis factor ligand superfamily member 13 (TNFSF13) also known as a proliferation-inducing ligand(APRIL) is a protein that in humans is encoded by the TNFSF13 gene. TNFSF13 has also been designated CD256(cluster of differentiation 256). The protein encoded by this gene is a member of the tumor necrosis factor ligand (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vivo experiments suggest an important role for APRIL in the long-term survival of plasma cells in the bone marrow. Mice deficient in April showed a reduced ability to support plasma cell survival In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such asTNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The TNFSF13 gene lies 878 bp downstream of the TNFSF12 gene on chromosome 17p13.1.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Andere Bezeichnung: TNFSF13/APRIL (TNFSF13 Produkte)

Synonyme: APRIL ELISA Kit, CD256 ELISA Kit, TALL-2 ELISA Kit, TALL2 ELISA Kit, TRDL-1 ELISA Kit, ZTNF2 ELISA Kit, 2310026N09Rik ELISA Kit, April ELISA Kit, Tall2 ELISA Kit, Trdl1 ELISA Kit, SLAN ELISA Kit, ANP32B ELISA Kit, april ELISA Kit, tnf13 ELISA Kit, TNLG7B ELISA Kit, TNF superfamily member 13 ELISA Kit, tumor necrosis factor (ligand) superfamily, member 13 ELISA Kit, acidic leucine-rich nuclear phosphoprotein 32 family member B ELISA Kit, TNFSF13 ELISA Kit, Tnfsf13 ELISA Kit, LOC494442 ELISA Kit, tnfsf13 ELISA Kit

Gen-ID: 8741

UniProt: Q2QBA2

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response