FCER2 ELISA Kit

Produktnummer ABIN2042392

Produktdetails FCER2 ELISA Kit

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Competition ELISA

Detektionsbereich: 31.2-2000 pg/mL

Untere Nachweisgrenze: 31.2 pg/mL

Applikation: ELISA

Marke: BioAssay™

Analytische Methode: Quantitative

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate pre-coated with anti-CD23/FCER2, Human
Lyophilized recombinant CD23/FCER2, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Human CD23/FCER2 in cell culture supernates, serum, plasma (heparin, EDTA) and urine.CD23, also known as Fc epsilon RII, or Fc RII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23 CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23(FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu FCER2

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Andere Bezeichnung: CD23/FCER2 (FCER2 Produkte)

Synonyme: BLAST-2 ELISA Kit, CD23 ELISA Kit, CD23A ELISA Kit, CLEC4J ELISA Kit, FCE2 ELISA Kit, IGEBF ELISA Kit, Fcer2a ELISA Kit, Fc fragment of IgE receptor II ELISA Kit, FCER2 ELISA Kit, Fcer2 ELISA Kit

Gen-ID: 2208

UniProt: K3W4U1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process