anti-Schwein Deoxynucleotidyltransferase, terminal Antikörper für Western Blotting

Recommended Deoxynucleotidyltransferase, terminal Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Deoxynucleotidyltransferase, terminal (DNTT) Antikörper
  • TdT
  • TDT
  • BB160593
  • Tdt
  • dntt-A
  • dntt
  • DNA nucleotidylexotransferase
  • deoxynucleotidyltransferase, terminal
  • DNA nucleotidylexotransferase L homeolog
  • terminal deoxynucleotidyl transferase
  • DNTT
  • dntt
  • Dntt
  • dntt.L
  • tdt
Epitop
N-Term
33
26
12
10
9
8
8
6
4
3
3
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
139
30
27
8
6
4
3
3
3
2
2
2
Wirt
Kaninchen
108
36
Klonalität
Polyklonal
Konjugat
Unkonjugiert
10
7
6
4
4
4
2
2
Applikation
Western Blotting (WB)
114
59
24
21
15
11
10
9
6
5
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2784740
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN321910 WB Rabbit IgG AA 32-81 Anmelden zum Anzeigen Polyclonal 0
1 ABIN469444 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN597977 WB Rabbit IgG AA 472-486 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Deoxynucleotidyltransferase, terminal (DNTT) Antikörper
Epitop N-Term
(33), (26), (12), (10), (9), (8), (8), (6), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
(139), (30), (27), (8), (6), (4), (3), (3), (3), (2), (2), (2)
Wirt Kaninchen
(108), (36)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(10), (7), (6), (4), (4), (4), (2), (2)
Applikation Western Blotting (WB)
(114), (59), (24), (21), (15), (11), (10), (9), (6), (5), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975939.
Sequenz FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
Homologie Cow: 100%, Dog: 79%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against DNTT. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DNTT

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung DNTT (DNTT Antibody Abstract)
Hintergrund DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: TDT
Protein Interaction Partner: REL, APOA1, DNTTIP1, UBC, PRPF19, DNTTIP2, PCNA, XRCC6, ABTB2, CUL3,
Protein Size: 509
Molekulargewicht 58 kDa
Gen-ID 1791
NCBI Accession NM_004088, NP_004079
UniProt P04053
Pathways DNA Reparatur

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 509 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Kubota, Maezawa, Koiwai, Hayano, Koiwai: "Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 12, Issue 8, pp. 941-59, 2007

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Deoxynucleotidyltransferase, terminal (DNTT) (N-Term) antibody (ABIN2784740) WB Suggested Anti-DNTT Antibody Titration: 0.2-1 ug/ml
Positive Control:...