anti-Claudin 12 (CLDN12) Antikörper

Bezeichnung:: anti-Claudin 12 Antikörper (CLDN12)

Auf www.antikoerper-online.de finden Sie aktuell 62 Claudin 12 (CLDN12) Antikörper von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Claudin 12 Kits (12) und Claudin 12 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 77 Claudin 12 Produkte verfügbar.

Synonyme:: claudin-12, CLDN12, DKFZp469F1620, RGD1561053, wu:fc27c11, wu:fc37h01, zgc:86588

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CLDN12	9069	P56749
	CLDN12	64945	Q9ET43
	CLDN12	500000
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Verknüpfte Pathways mit anti-Claudin 12 Antikörper

Cell-Cell Junction Organization

Weitere Produktkategorien zu Claudin 12 Antikörper

Am meisten referenzierte anti-Claudin 12 Antikörper

Human Polyclonal CLDN12 Primary Antibody für IF (p), IHC (p) - ABIN2173111 : Sadowska, Ahmedli, Chen, Stonestreet: Ontogeny of tight junction protein expression in the ovine cerebral cortex during development. in Neuroscience 2015 (PubMed)

Weitere Antikörper gegen Claudin 12 Interaktionspartner

Human Claudin 12 (CLDN12) Interaktionspartner

CLDN 12 expression could be clinically useful for predicting the survival of the estrogen receptor (ER (zeige ESR1 Antikörper))-negative subgroup of patients with breast cancer.
Knockdown of claudin-3 (zeige CLDN3 Antikörper), claudin-4 (zeige CLDN4 Antikörper), and claudin-12, but not claudin-1 (zeige CLDN7 Antikörper), increased breast cancer MCF-7 cell migration with maximal effects observed in claudin-12 siRNA-transfected cells.
These findings strongly suggest that claudin-2 (zeige CLDN2 Antikörper)- and/or claudin-12-based tight junctions form paracellular Ca(2 (zeige CA2 Antikörper)+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis.

Mouse (Murine) Claudin 12 (CLDN12) Interaktionspartner

Claudin-12 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area.
1,25(OH)2D3 downregulates cadherin-17 and upregulates claudin-2 (zeige CLDN2 Antikörper) and claudin-12 in the intestine, suggesting that 1,25(OH)2D3, by regulating these epithelial cell junction proteins, can route calcium through the paracellular path
These findings strongly suggest that claudin-2 (zeige CLDN2 Antikörper)- and/or claudin-12-based tight junctions form paracellular Ca(2 (zeige CA2 Antikörper)+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis.

Claudin 12 (CLDN12) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.

Alternative names and synonyms associated with Claudin 12 (CLDN12)

claudin 12 (CLDN12) Antikörper
claudin 12 (cldn12) Antikörper
claudin 12 (Cldn12) Antikörper
claudin 12 S homeolog (cldn12.S) Antikörper
claudin 12 (CpipJ_CPIJ011954) Antikörper

claudin-12 Antikörper
CLDN12 Antikörper
DKFZp469F1620 Antikörper
RGD1561053 Antikörper
wu:fc27c11 Antikörper
wu:fc37h01 Antikörper
zgc:86588 Antikörper

Bezeichner auf Proteinebene für anti-Claudin 12 (CLDN12) Antikörper

claudin 12 , claudin-12 , claudin-12-like

GENE ID	SPEZIES
100174503	Pongo abelii
549605	Xenopus (Silurana) tropicalis
9069	Homo sapiens
64945	Mus musculus
81593	Danio rerio
463521	Pan troglodytes
496360	Xenopus laevis
500000	Rattus norvegicus
538709	Bos taurus
608397	Canis lupus familiaris
704058	Macaca mulatta
771872	Gallus gallus
6044554	Culex quinquefasciatus
100060361	Equus caballus
100137459	Papio anubis
100294674	Sus scrofa
100328633	Oryctolagus cuniculus
100391361	Callithrix jacchus
101108741	Ovis aries
100730214	Cavia porcellus

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Show all anti-Claudin 12 (CLDN12) Antikörper with Pubmed References

Human Claudin 12 (CLDN12) Interaktionspartner

Mouse (Murine) Claudin 12 (CLDN12) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Claudin 12 (CLDN12)

Bezeichner auf Proteinebene für anti-Claudin 12 (CLDN12) Antikörper