Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
CCR6 facilitates tumor angiogenesis via the AKT (zeige AKT1 Proteine)/NF-kappaB (zeige NFKB1 Proteine)/VEGF (zeige VEGFA Proteine) pathway in colorectal cancer
In conclusion, it seems that decreased expression of CXCR3 (zeige CXCR3 Proteine) and higher expression of CCR6 were associated with HTLV-1 infection, what indicate that these alterations may favor virus dissemination but not disease manifestation.
Bin1 (zeige BIN1 Proteine)-N-BAR domains assemble into scaffolds of low long-range order that form flexible membrane tubule in the sarcolemma
CCR6 defines memory B cell precursors in mouse and human germinal centers, revealing light-zone location and predominant low antigen affinity.
High expression of CCR6 is associated with cutaneous T-cell lymphoma.
CCR6(-) regulatory T cells blunt the restoration of gut (zeige GUSB Proteine) Th17 cells along the CCR6-CCL20 (zeige CCL20 Proteine) axis in treated HIV-1-infected patients.
results provide a potential explanation for involvement of the CCL20 (zeige CCL20 Proteine)-CCR6 system in the trafficking of IL-17 (zeige IL17A Proteine)-producing cells to degenerated IVD (zeige IVD Proteine) tissues
The percentage of CXCR3 (zeige CXCR3 Proteine)(+) CD4 (zeige CD4 Proteine)(+) TEM (zeige CYLD Proteine) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (zeige SELPLG Proteine)(+) CD4 (zeige CD4 Proteine)(+) TCM cells expressing CCR6(+) or CCR4 (zeige CCR4 Proteine)(+)CXCR3 (zeige CXCR3 Proteine)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.
High CCR6 expression is associated with B-lymphoblastic lymphoma with inflammation.
CCR6 expression was higher in cells derived from node-positive cases and highest expression was in cells derived from metastatic cases of colon cancer.
Study identified protein and gene expression of chemokine receptor 6 in the hippocampus of Swiss mice with immunohistochemistry and RT-PCR, showed that CCR6 may be involved in normal neuronal activity in the hippocampus and play an important role in maintenance of the status epilepticus.
these data indicate that CCL20 (zeige CCL20 Proteine)/CCR6 signaling may play an important role in regulating bone mass accrual, potentially by modulating osteoblast maturation, survival, and the recruitment of osteoblast-supporting cells.
CCR6 is upregulated rapidly within hours on the protein or mRNA level after activation in vitro.
These findings identify a crucial role for CCR6 in promoting LP-mononuclear phagocytes to associate with the intestinal epithelium in the steady state to perform multiple functions promoting gut (zeige GUSB Proteine) immune homeostasis.
data suggest that gammadeltaT17 cells are completely dependent on CCR6 for homing to psoriasiform skin. Thus, CCR6 may constitute a novel target for a mechanistically distinct therapeutic approach to treating psoriasis.
Data (including data from studies using knockout mice or cells from knockout mice) suggest that HuR (zeige ELAVL1 Proteine) post-transcriptionally regulates Ccr6 expression by binding to and stabilizing Ccr6 mRNA and by promoting Ccr6 translation in helper T-cells; knock-out of HuR (zeige ELAVL1 Proteine) reduces Ccr6 expression on helper T-cells, impairs their migration to CNS, and prevents experimental autoimmune encephalomyelitis. (HuR (zeige ELAVL1 Proteine) = Hu antigen R (zeige ELAVL1 Proteine))
CCR6 deficiency affects hepatic inflammatory cell recruitment resulting in the promotion of hepatic inflammation and fibrosis.
in mice, activated B cells use the chemokine receptor CCR6 to access the subepithelial dome (SED) of Peyer's patches.
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
chemokine (C-C motif) receptor 6
, C-C chemokine receptor type 6
, CC chemokine receptor 6
, c-C chemokine receptor type 6-like
, G protein-coupled receptor 29
, G-protein coupled receptor 29
, LARC receptor
, chemokine (C-C) receptor 6
, chemokine receptor-like 3
, seven-transmembrane receptor, lymphocyte, 22