SNCG (Breast Cancer-Specific Protein 1) Antikörper

Produktnummer ABIN969490

Produktdetails

Target: SNCG (Breast Cancer-Specific Protein 1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of SNCG expressed in E. coli.

Klon: 1H10D2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen

Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

Brown, Lasek: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." in: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).

Antigendetails

Target: SNCG (Breast Cancer-Specific Protein 1)

Hintergrund:

Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Aliases: SR, BCSG1

Gen-ID: 6623

HGNC: 6623