ERK2 Antikörper (C-Term)

Produktnummer ABIN966091

Produktdetails anti-ERK2 Antikörper

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 1 (MAPK1) detection. Tested with WB in Human, Mouse, Rat.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human ERK2, identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Referenzen für anti-ERK2 Antikörper (ABIN966091)

Oliveira, Rigon, Leal, Rossi: "The activation of ERK1/2 and p38 mitogen-activated protein kinases is dynamically regulated in the developing rat visual system." in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, Vol. 26, Issue 3-4, pp. 355-62, (2008) (PubMed).

Forcet, Stein, Pays, Corset, Llambi, Tessier-Lavigne, Mehlen: "Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation." in: Nature, Vol. 417, Issue 6887, pp. 443-7, (2002) (PubMed).

Di Cristo, Berardi, Cancedda, Pizzorusso, Putignano, Ratto, Maffei: "Requirement of ERK activation for visual cortical plasticity." in: Science (New York, N.Y.), Vol. 292, Issue 5525, pp. 2337-40, (2001) (PubMed).

Khokhlatchev, Canagarajah, Wilsbacher, Robinson, Atkinson, Goldsmith, Cobb: "Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation." in: Cell, Vol. 93, Issue 4, pp. 605-15, (1998) (PubMed).

Li, Wysk, Gonzalez, Davis: "Genomic loci of human mitogen-activated protein kinases." in: Oncogene, Vol. 9, Issue 2, pp. 647-9, (1994) (PubMed).

Owaki, Makar, Boulton, Cobb, Geppert: "Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs." in: Biochemical and biophysical research communications, Vol. 182, Issue 3, pp. 1416-22, (1992) (PubMed).

Details zu ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Abstract: MAPK1 Produkte

Synonyme: ERK-1 antikoerper, ERK1 antikoerper, ERT2 antikoerper, HS44KDAP antikoerper, HUMKER1A antikoerper, P44ERK1 antikoerper, P44MAPK antikoerper, PRKM3 antikoerper, p44-ERK1 antikoerper, p44-MAPK antikoerper, Erk-1 antikoerper, Erk1 antikoerper, Ert2 antikoerper, Esrk1 antikoerper, Mnk1 antikoerper, Mtap2k antikoerper, Prkm3 antikoerper, p44 antikoerper, p44erk1 antikoerper, p44mapk antikoerper, ERK antikoerper, ERK2 antikoerper, ERT1 antikoerper, MAPK2 antikoerper, P42MAPK antikoerper, PRKM1 antikoerper, PRKM2 antikoerper, p38 antikoerper, p40 antikoerper, p41 antikoerper, p41mapk antikoerper, 9030612K14Rik antikoerper, AA407128 antikoerper, AU018647 antikoerper, C78273 antikoerper, Erk2 antikoerper, Prkm1 antikoerper, p42mapk antikoerper, zERK2 antikoerper, MAPK1 antikoerper, Xp42 antikoerper, erk antikoerper, erk2 antikoerper, ert1 antikoerper, mapk antikoerper, mapk1b antikoerper, mapk2 antikoerper, mpk1 antikoerper, prkm1 antikoerper, prkm2 antikoerper, mapk1 antikoerper, mapk1a antikoerper, xp42 antikoerper, ATMPK1 antikoerper, F14N23.9 antikoerper, F14N23_9 antikoerper, MITOGEN-ACTIVATED PROTEIN KINASE antikoerper, mitogen-activated protein kinase 1 antikoerper, MNK1 antikoerper, ATMPK2 antikoerper, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antikoerper, T30E16.13 antikoerper, T30E16_13 antikoerper, mitogen-activated protein kinase homolog 2 antikoerper, mitogen-activated protein kinase 3 antikoerper, mitogen-activated protein kinase 1 antikoerper, mitogen activated protein kinase 1 antikoerper, mitogen-activated protein kinase 1 L homeolog antikoerper, mitogen-activated protein kinase 1 S homeolog antikoerper, mitogen activated protein kinase 3 antikoerper, mitogen-activated protein kinase homolog 2 antikoerper, MAPK3 antikoerper, Mapk3 antikoerper, MAPK1 antikoerper, Mapk1 antikoerper, mapk1 antikoerper, mapk1.L antikoerper, mapk1.S antikoerper, PfMAP1 antikoerper, MPK1 antikoerper, PVX_084965 antikoerper, LOC9328617 antikoerper, Tsp_01601 antikoerper, MPK2 antikoerper

Hintergrund: Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme which in humans is encoded by the MAPK1 gene. The gene is mapped to 22q11. 2. And The protein encoded by this gene is a member of the MAP kinase family. The deduced 360-amino acid human ERK2 protein shares 98 % identity with rat Erk2. The MAP kinase ERK2 is widely involved in eukaryotic signal transduction. Upon activation, it translocates to the nucleus of the stimulated cell, where it phosphorylates nuclear targets. Futhermore, the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex. And the MAPK pathway is also involved in responses to NTN1.

Pathways: MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteine