CST3 Antikörper (C-Term)

Produktnummer ABIN965952

Produktdetails anti-CST3 Antikörper

Target: CST3 (Cystatin C (CST3))

Bindungsspezifität: AA 45-63, C-Term

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Polyklonal

Konjugat: Dieser CST3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human Cystatin C (45-63aa), identical to the related mouse and rat sequence.

Anwendungsinformationen

Applikationshinweise: WB: The detection limit for Cystatin C is approximately 2.5ng/lane under non-reducing and reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Lagerung: -20 °C

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: Cystatin C (CST3 Produkte)

Synonyme: armd11 antikoerper, fb51d07 antikoerper, wu:fb24g06 antikoerper, wu:fb51d07 antikoerper, wu:fc55f03 antikoerper, zgc:136227 antikoerper, ARMD11 antikoerper, CysC antikoerper, CYSC antikoerper, cystatin C antikoerper, cystatin C L homeolog antikoerper, cystatin C (amyloid angiopathy and cerebral hemorrhage) antikoerper, cystatin 3 antikoerper, CST3 antikoerper, cst3.L antikoerper, cst3 antikoerper, cystatin 3 antikoerper, Cst3 antikoerper

Hintergrund: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. By human-rodent somatic cell hybridizations, Abrahamson et al. (1989) mapped the human CST3 to chromosome 20. Cystatin C was originally described as a constituent of normal cerebrospinal fluid (CSF) and of urine from patients with renal failure (Grubb and Lofberg, 1982). It is present in a number of neuroendocrine cells and its concentration in the CSF was reported to be 5.5 times that in plasma of healthy adults (Lofberg and Grubb, 1979, Lofberg et al., 1981, Lofberg et al., 1983). Grubb and Lofberg detected the protein in human pituitary gland, and suggested that it is part of the gastroenteropancreatic neuroendocrine system.