Cathelicidin Antikörper

Produktnummer ABIN965742

Produktdetails anti-Cathelicidin Antikörper

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Reaktivität: Bitte anfragen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathelicidin Antikörper ist unkonjugiert

Applikation: ELISA

Aufreinigung: Ascitic fluid

Immunogen: cAMP, conjugated to KLH.

Klon: 9H4C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Cathelicidin Antikörper (ABIN965742)

J: "[SOFMER, its topicality and its prospects]." in: Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique, Vol. 51, Issue 5, pp. 329-31, (2008) (PubMed).

Details zu Cathelicidin

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Andere Bezeichnung: cAMP (CAMP Produkte)

Synonyme: CAP-18 antikoerper, CAP18 antikoerper, CRAMP antikoerper, FALL-39 antikoerper, FALL39 antikoerper, LL37 antikoerper, CATH-2 antikoerper, Cnlp antikoerper, Cramp antikoerper, MCLP antikoerper, CATH-B1 antikoerper, CATHB1 antikoerper, CATHL2 antikoerper, CATHL7 antikoerper, CAP11 antikoerper, cathelicidin antimicrobial peptide antikoerper, CAMP antikoerper, LOC100136187 antikoerper, LOC100136439 antikoerper, Camp antikoerper

Substanzklasse: Chemical

Hintergrund: Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery
Synonyms: cAMP

Pathways: Cellular Response to Molecule of Bacterial Origin