SNTB2 Antikörper (Middle Region)

Produktnummer ABIN955046

Produktdetails anti-SNTB2 Antikörper

Target: SNTB2 (Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))

Bindungsspezifität: AA 216-245, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNTB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects human Syntrophin-3 / SNTB2.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a protein A column,; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 216-245aa) of human Syntrophin-3 / SNTB2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SNTB2

Target: SNTB2 (Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))

Andere Bezeichnung: Syntrophin-3 / SNTB2 (SNTB2 Produkte)

Synonyme: Snt2 antikoerper, D16S2531E antikoerper, EST25263 antikoerper, SNT2B2 antikoerper, SNT3 antikoerper, SNTL antikoerper, syntrophin, basic 2 antikoerper, syntrophin beta 2 antikoerper, Sntb2 antikoerper, SNTB2 antikoerper

Hintergrund: Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 basic component 2, Beta-2-syntrophin, SNT2B2, SNT3, SNTL, Syntrophin-like

Gen-ID: 6645

NCBI Accession: NP_006741