POU3F1 Antikörper (Internal Region)

Produktnummer ABIN954257

Produktdetails anti-POU3F1 Antikörper

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser POU3F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-HHALHEDGHE AQLE

Spezifität: This antibody recognizes OCT6

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002690.3. Genename: POU3F1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu POU3F1

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Andere Bezeichnung: POU3F1 / OCT6 (POU3F1 Produkte)

Synonyme: OCT6 antikoerper, OTF6 antikoerper, SCIP antikoerper, Oct-6 antikoerper, Oct6 antikoerper, Otf-6 antikoerper, Otf6 antikoerper, Scip antikoerper, Test1 antikoerper, Tst-1 antikoerper, Tst1 antikoerper, pou50 antikoerper, wu:fc09d06 antikoerper, zp-50 antikoerper, zp50 antikoerper, zp50pou antikoerper, Testes-1 antikoerper, Xlnrl-34 antikoerper, nrl-22 antikoerper, nrl-34 antikoerper, nrl34-A antikoerper, oct-6 antikoerper, oct6 antikoerper, pou3f1 antikoerper, scip antikoerper, pou1-A antikoerper, POU class 3 homeobox 1 antikoerper, POU domain, class 3, transcription factor 1 antikoerper, POU class 3 homeobox 1 L homeolog antikoerper, POU class 3 homeobox 1 S homeolog antikoerper, POU3F1 antikoerper, Pou3f1 antikoerper, pou3f1 antikoerper, pou3f1.L antikoerper, pou3f1.S antikoerper

Hintergrund: POU homeodomain proteins are transcriptional regulators that function in various developmental processes (e.g. cell division, differentiation, specification and survival of specific cell types) and participate in the determination of cell fate. The 45 kDa POU transcription factor Oct-6 (also designated SCIP and Tst-1) is expressed by late embryonic Schwann cells of the peripheral nervous system and is also expressed by nonmyelinating Schwann cells in adults. Oct-6 is strongly upregulated in promyelin cells because it is required for the timely differentiation of promyelin cells into myelinating cells. Oct-6 functions during myelination and is required for the proper downregulation of its own gene when myelination proceeds. c-Myc can act synergistically with the POU domain of Oct-6 to produce myelin disease pathogenesis in the mammalian central nervous system.Synonyms: OTF6, Oct-6, Octamer-binding protein 6, Octamer-binding transcription factor 6, POU domain class 3 transcription factor 1, POU domain transcription factor SCIP, SCIP

Gen-ID: 5453

NCBI Accession: NP_002690