PLGF Antikörper (AA 24-158)

Produktnummer ABIN954169

Produktdetails anti-PLGF Antikörper

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Bindungsspezifität: AA 24-158

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Recognizes PlGF.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Protein A Chromatography

Endotoxin-Niveau: < 0.1 EU/1 μg of the antibody (LAL)

Immunogen: Highly pure (>95%) recombinant Mouse PlGF (Ala24-Pro158) derived from Sf9 insect cells.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!

Haltbarkeit: 6 months

Referenzen für anti-PLGF Antikörper (ABIN954169)

Bader, Hsu: "Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model." in: BMC cancer, Vol. 16, Issue 1, pp. 797, (2017) (PubMed).

Details zu PLGF

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Andere Bezeichnung: Placenta Growth Factor / PGF (PGF Produkte)

Synonyme: D12S1900 antikoerper, PGFL antikoerper, PLGF antikoerper, PlGF-2 antikoerper, SHGC-10760 antikoerper, AI854365 antikoerper, PIGF antikoerper, Plgf antikoerper, PlGF antikoerper, placental growth factor antikoerper, placenta growth factor antikoerper, PGF antikoerper, Pgf antikoerper, PLGF antikoerper

Hintergrund: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65 % amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.Synonyms: PGFL, PLGF, PlGF

Gen-ID: 18654

NCBI Accession: NP_032853

Pathways: VEGFR1 Specific Signals