LZTS1 Antikörper (N-Term)

Produktnummer ABIN953266

Produktdetails anti-LZTS1 Antikörper

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Bindungsspezifität: AA 76-105, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LZTS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human LZTS1 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 76-105 amino acids from the N-terminal region of human LZTS1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Andere Bezeichnung: LZTS1 (LZTS1 Produkte)

Synonyme: F37 antikoerper, FEZ1 antikoerper, Psdzip70 antikoerper, LZTS1 antikoerper, f37 antikoerper, fez1 antikoerper, leucine zipper tumor suppressor 1 antikoerper, leucine zipper, putative tumor suppressor 1 antikoerper, LZTS1 antikoerper, Lzts1 antikoerper, lzts1 antikoerper

Hintergrund: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.Synonyms: F37/esophageal cancer-related gene-coding leucine-zipper motif, FEZ1, LZTS1, Leucine zipper putative tumor suppressor 1

Molekulargewicht: 66613 Da

Gen-ID: 11178

NCBI Accession: NP_066300

Pathways: Synaptic Membrane