KCNQ3 Antikörper (C-Term)

Produktnummer ABIN953015

Produktdetails anti-KCNQ3 Antikörper

Target: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Bindungsspezifität: AA 650-679, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse KCNQ3 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 650-679 amino acids from the C-terminal region of human KCNQ3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KCNQ3

Target: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Andere Bezeichnung: KCNQ3 (KCNQ3 Produkte)

Synonyme: KCNQ3 antikoerper, si:ch211-66b9.3 antikoerper, BFNC2 antikoerper, EBN2 antikoerper, KV7.3 antikoerper, potassium voltage-gated channel subfamily Q member 3 antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 3 antikoerper, potassium voltage-gated channel, subfamily Q, member 3 antikoerper, KCNQ3 antikoerper, kcnq3 antikoerper, Kcnq3 antikoerper

Hintergrund: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).Synonyms: KQT-like 3, Potassium channel subunit alpha KvLQT3, Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3

Molekulargewicht: 96742 Da

Gen-ID: 3786

NCBI Accession: NP_001191753