Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR) (AA 101-130), (N-Term) Antikörper

Details zu Produkt Nr. ABIN951873, Anbieter: Anmelden zum Anzeigen
Antigen
  • DAP4
  • P52rIPK
  • THAP0
  • THAP12
  • 2900052B10Rik
  • Dap4
  • Rpkrir
  • dap4
  • p52ripk
  • MGC75860
  • PRKRIR
  • prkrir
  • prkrir.S
  • THAP domain containing 12
  • THAP domain containing 12 S homeolog
  • THAP12
  • Thap12
  • thap12
  • thap12.S
Epitop
N-Term, AA 101-130
10
9
8
5
4
3
2
1
1
Reaktivität
Human
47
12
8
4
4
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
41
6
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
5
5
2
2
2
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
39
27
6
5
4
3
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 101-130 amino acids from the N-terminal region of human PRKRIR
Isotyp Ig Fraction
Spezifität This antibody reacts to TRKRIR.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Andere Bezeichnung Death-Associated Protein 4 (PRKRIR Antibody Abstract)
Hintergrund Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.Synonyms: 52 kDa repressor of the inhibitor of the protein kinase, DAP4, P52RIPK, PRKRIR, THAP domain-containing protein 0, THAP0, p58IPK-interacting protein
Molekulargewicht 87704 Da
Gen-ID 5612
NCBI Accession NP_004696
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR) (AA 101-130), (N-Term) antibody (ABIN951873) PRKRIR Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35µg/lane)...
Allgemeine Veröffentlichungen Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, 2010 (PubMed).

Lin, Khokhlatchev, Figeys, Avruch: "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 47991-8001, 2002 (PubMed).

Saelens, Kalai, Vandenabeele: "Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation." in: The Journal of biological chemistry, Vol. 276, Issue 45, pp. 41620-8, 2001 (PubMed).

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