CHD1L antikoerper, ALC1 antikoerper, CHDL antikoerper, 4432404A22Rik antikoerper, Alc1 antikoerper, Snf2p antikoerper, zgc:56084 antikoerper, chromodomain helicase DNA binding protein 1 like antikoerper, chromodomain helicase DNA binding protein 1-like antikoerper, CHD1L antikoerper, chd1l antikoerper, Chd1l antikoerper
Hintergrund
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].Synonyms: ALC1, Amplified in liver cancer protein 1, Chromodomain-helicase-DNA-binding protein 1-like