CHD1L Antikörper (Middle Region)

Produktnummer ABIN951497

Produktdetails anti-CHD1L Antikörper

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Bindungsspezifität: AA 560-590, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CHD1L.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 560-590 amino acids from the Central region of human CHD1L

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHD1L

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Andere Bezeichnung: CHD1L (CHD1L Produkte)

Synonyme: CHD1L antikoerper, ALC1 antikoerper, CHDL antikoerper, 4432404A22Rik antikoerper, Alc1 antikoerper, Snf2p antikoerper, zgc:56084 antikoerper, chromodomain helicase DNA binding protein 1 like antikoerper, chromodomain helicase DNA binding protein 1-like antikoerper, CHD1L antikoerper, chd1l antikoerper, Chd1l antikoerper

Hintergrund: In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].Synonyms: ALC1, Amplified in liver cancer protein 1, Chromodomain-helicase-DNA-binding protein 1-like

Molekulargewicht: 78kd Isoform 3. 100984 Da

Gen-ID: 9557

NCBI Accession: NP_004275