ARHGEF6 Antikörper (C-Term)

Produktnummer ABIN950497

Produktdetails anti-ARHGEF6 Antikörper

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Bindungsspezifität: AA 613-641, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ARHGEF6.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ARHGEF6

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ARHGEF6

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Andere Bezeichnung: ARHGEF6 (ARHGEF6 Produkte)

Synonyme: COOL2 antikoerper, Cool-2 antikoerper, MRX46 antikoerper, PIXA antikoerper, alpha-PIX antikoerper, alphaPIX antikoerper, 1600028C08Rik antikoerper, 1700038J06Rik antikoerper, 4930592P22Rik antikoerper, Rac/Cdc42 guanine nucleotide exchange factor 6 antikoerper, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antikoerper, ARHGEF6 antikoerper, Arhgef6 antikoerper

Hintergrund: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.Synonyms: Alpha-Pix, COOL-2, COOL2, KIAA0006, PAK-interacting exchange factor alpha, PIXA, Rac/Cdc42 guanine nucleotide exchange factor 6, Rho guanine nucleotide exchange factor 6

Gen-ID: 9459

NCBI Accession: NP_004831

Pathways: Neurotrophin Signalübertragung