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APP Antikörper
APP
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-APP Antikörper
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Target
Alle APP Antikörper anzeigen
APP
(Amyloid beta (A4) Precursor Protein (APP))
Reaktivität
Alle Reaktivitäten für APP Antikörper
Human
Wirt
Alle Wirte für APP Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für APP Antikörper
Polyklonal
Konjugat
Alle Konjugate für APP Antikörper
Dieser APP Antikörper ist unkonjugiert
Applikation
Alle Applikationen für APP Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to Amyloid beta A4 protein.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography on Protein G
Immunogen
KLH conjugated synthetic peptide selected from the Y756 region of human APP
Isotyp
Ig Fraction
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu APP
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Target
APP
(Amyloid beta (A4) Precursor Protein (APP))
Andere Bezeichnung
Amyloid beta A4 Protein / APP (APP Produkte )
Synonyme
AAA antikoerper, ABETA antikoerper, ABPP antikoerper, AD1 antikoerper, APPI antikoerper, CTFgamma antikoerper, CVAP antikoerper, PN-II antikoerper, PN2 antikoerper, aaa antikoerper, abeta antikoerper, abpp antikoerper, ad1 antikoerper, appi antikoerper, ctfgamma antikoerper, cvap antikoerper, pn2 antikoerper, APP antikoerper, APP-like antikoerper, APPL antikoerper, Abeta antikoerper, BcDNA:GH04413 antikoerper, CG7727 antikoerper, Dmel\\CG7727 antikoerper, EG:65F1.5 antikoerper, appl antikoerper, Abpp antikoerper, Adap antikoerper, Ag antikoerper, Cvap antikoerper, E030013M08Rik antikoerper, betaApp antikoerper, app antikoerper, wu:fj34d10 antikoerper, wu:fk65e12 antikoerper, zgc:85740 antikoerper, amyloid beta precursor protein antikoerper, amyloid beta (A4) precursor protein antikoerper, beta amyloid protein precursor-like antikoerper, amyloid beta (A4) precursor protein a antikoerper, amyloid beta precursor protein L homeolog antikoerper, APP antikoerper, app antikoerper, Appl antikoerper, App antikoerper, appa antikoerper, app.L antikoerper
Hintergrund
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Synonyms: ABPP, APPI, Alzheimer disease amyloid protein, Amyloid Precursor Protein, CVAP, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II
Gen-ID
351
NCBI Accession
NP_000475
Pathways
Caspase Kaskade in der Apoptose , EGFR Signaling Pathway , Transition Metal Ion Homeostasis , Skeletal Muscle Fiber Development , Toll-Like Receptors Cascades , Feeding Behaviour
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