ADRA1B Antikörper (Middle Region)

Produktnummer ABIN950364

Produktdetails anti-ADRA1B Antikörper

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Bindungsspezifität: AA 276-306, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Alpha-1B adrenergic receptor.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ADRA1B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Andere Bezeichnung: alpha-1B Adrenergic Receptor (ADRA1B Produkte)

Synonyme: LOC100136712 antikoerper, [a]1b antikoerper, ADRA1 antikoerper, ALPHA1BAR antikoerper, RDC5 antikoerper, alpha-1B adrenoceptor antikoerper, adrenoceptor alpha 1B antikoerper, adrenergic receptor, alpha 1b antikoerper, LOC100136712 antikoerper, ADRA1B antikoerper, Adra1b antikoerper

Hintergrund: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.Synonyms: ADRA1B, Alpha 1B-adrenoceptor, Alpha 1B-adrenoreceptor

Gen-ID: 147

NCBI Accession: NP_000670

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process