Actin Antikörper (C-Term)

Produktnummer ABIN950357

Produktdetails anti-Actin Antikörper

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Bindungsspezifität: AA 345-376, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Actin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to alpha skeletal muscle Actin.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 345-376 amino acids from the C-terminal region of human ACTA1/alpha-actin

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Actin

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Andere Bezeichnung: alpha Skeletal Muscle Actin / ACTA1 (ACTA1 Produkte)

Synonyme: ACTA antikoerper, ASMA antikoerper, CFTD antikoerper, CFTD1 antikoerper, CFTDM antikoerper, MPFD antikoerper, NEM1 antikoerper, NEM2 antikoerper, NEM3 antikoerper, acta antikoerper, asma antikoerper, cftd antikoerper, cftd1 antikoerper, cftdm antikoerper, mpfd antikoerper, nem1 antikoerper, AA959943 antikoerper, Acta-2 antikoerper, Acts antikoerper, Actsk-1 antikoerper, actc antikoerper, actc1 antikoerper, cfk antikoerper, hm:zeh0631 antikoerper, zeh0631 antikoerper, acta1 antikoerper, hm:zeh0293 antikoerper, zgc:112098 antikoerper, actin, alpha 1, skeletal muscle antikoerper, actin, alpha 1, skeletal muscle L homeolog antikoerper, actin, alpha 1b, skeletal muscle antikoerper, actin, muscle antikoerper, actin, alpha skeletal muscle antikoerper, actin, alpha 1a, skeletal muscle antikoerper, ACTA1 antikoerper, acta1.L antikoerper, acta1 antikoerper, Acta1 antikoerper, acta1b antikoerper, LOC100533357 antikoerper, LOC109479779 antikoerper, LOC109108280 antikoerper, acta1a antikoerper

Hintergrund: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Gen-ID: 58

NCBI Accession: NP_001091

Pathways: Caspase Kaskade in der Apoptose, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development