AKR1C2 Antikörper (C-Term)

Produktnummer ABIN950320

Produktdetails anti-AKR1C2 Antikörper

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Bindungsspezifität: AA 295-323, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to AKR1C2.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 295-323 amino acids from the C-terminal region of human AKR1C2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Andere Bezeichnung: AKR1C2 / DDH2 (AKR1C2 Produkte)

Synonyme: AKR1C-pseudo antikoerper, BABP antikoerper, DD antikoerper, DD2 antikoerper, DDH2 antikoerper, HAKRD antikoerper, HBAB antikoerper, MCDR2 antikoerper, SRXY8 antikoerper, Akr1c21 antikoerper, aldo-keto reductase family 1 member C2 antikoerper, aldo-keto reductase family 1, member C2 antikoerper, AKR1C2 antikoerper, Akr1c2 antikoerper

Hintergrund: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.Synonyms: 2-dihydrobenzene-1, 2-diol dehydrogenase, 3-alpha-HSD3, Aldo-keto reductase family 1 member C2, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, Dihydrodiol dehydrogenase/bile acid-binding protein, Trans-1, Type III 3-alpha-hydroxysteroid dehydrogenase

Molekulargewicht: 36735 Da

Gen-ID: 1646

NCBI Accession: NP_001345

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process