ADIPOQ Antikörper

Produktnummer ABIN950284

Produktdetails anti-ADIPOQ Antikörper

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ADIPOQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects Mouse Adiponectin. It is crossreactive to Human Adiponectin protein in Western blotting.

Aufreinigung: Protein A/G Affinity Chromatography

Sterilität: 0.2 μm filtered

Immunogen: Purified Mouse Recombinant Adiponectin.

Klon: 7J61

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL

Buffer: 0.2 μm filtered solution in PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.

Haltbarkeit: 6 months

Details zu ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Andere Bezeichnung: Adiponectin (ADIPOQ Produkte)

Synonyme: ADP antikoerper, DCAF9 antikoerper, 6720489L24Rik antikoerper, 9330209L04Rik antikoerper, Adp antikoerper, Mamdc1 antikoerper, RNSVSP4U antikoerper, SVSIV1 antikoerper, Svp4 antikoerper, ACDC antikoerper, ACRP30 antikoerper, ADIPQTL1 antikoerper, ADPN antikoerper, APM-1 antikoerper, APM1 antikoerper, GBP28 antikoerper, apM-1 antikoerper, 30kDa antikoerper, APN antikoerper, Acdc antikoerper, Acrp30 antikoerper, Ad antikoerper, adipo antikoerper, apM1 antikoerper, ADN antikoerper, acrpl antikoerper, adipo-b antikoerper, adipoql antikoerper, zgc:153584 antikoerper, adipoq antikoerper, WD and tetratricopeptide repeats 1 antikoerper, MAM domain containing glycosylphosphatidylinositol anchor 2 antikoerper, seminal vesicle secretory protein 4 antikoerper, adiponectin, C1Q and collagen domain containing antikoerper, adiponectin, C1Q and collagen domain containing, b antikoerper, adiponectin, C1Q and collagen domain containing L homeolog antikoerper, WDTC1 antikoerper, Mdga2 antikoerper, Svs4 antikoerper, ADIPOQ antikoerper, Adipoq antikoerper, adipoqb antikoerper, adipoq.L antikoerper

Hintergrund: Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. In this context, adiponectin is an antiinflammatory agent, but it exerts proinflammatory effects in nonmetabolic disorders such as rheumatoid arthritis and inflammatory bowel disease. Adiponectin interacts with the receptors AdipoR1 and AdipoR2, calreticulin, and Cadherin13/ T-Cadherin, as well as with several growth factors. Mature mouse adiponectin consists of a 66 amino acid (aa) N-terminal collagenous region and a 137 aa C terminal C1q like globular domain which can be cleaved by a leukocytederived elastase. Mature mouse adiponectin shares 83 % and 91 % amino acid (aa) sequence identity with human and rat adiponectin, respectively. Adiponectin associates into trimers that may assemble into medium molecular weight (MMW) hexamers and then into >300 kDa high molecular weight (HMW) oligomers. The glycosylation of four hydroxylated lysine residues in the collagenous domain is required for the intracellular formation of HMW complexes. The various multimeric forms of adiponectin exhibit distinct tissue specific and gender specific profiles and activities.Synonyms: 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPOQ, APM1, Adipocyte, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, C1q and collagen domain-containing protein, GBP28, Gelatin-binding protein

Gen-ID: 11450

NCBI Accession: NP_033735

UniProt: Q60994