Binds to recombinant rev (HIV-1 HxB2, HxB3) in ELISA and Western Blot. The antibody is epitope mapped to rev (70-84).
Aufreinigung
purified
Klon
9G2G4D6E8
Isotyp
IgG2b
Applikationshinweise
ELISA: 1:500-1:1,000, WB: 1:500-1:1,000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Konzentration
Lot specific
Buffer
Supplied lyophilized as a purified IgG in PBS buffer, with no preservatives added.
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
Store lyophilized product at 2-8 °C short term, following reconstitution, aliquot and store at -70 °C or lower.
Target
Rev
Substanzklasse
Viral Protein
Hintergrund
Rev is a HIV gene. The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced, in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced. Synonyms: Monoclonal HIV1 Rev antibody, Anti-HIV1 Rev antibody, Anti-repression transactivator protein antibody, art/trs antibody, HIV1gp6 antibody, Human immunodeficiency virus 1 Rev antibody, Protein Rev antibody, Regulator of expression of viral proteins antibody, Rev antibody.