CYP2A6 Antikörper (C-Term)

Produktnummer ABIN929448

Produktdetails anti-CYP2A6 Antikörper

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: CYP2 A6 antibody was raised in rabbit using the C terminal of CYP2 6 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CYP2A6 Blocking Peptide, catalog no. 33R-1182, is also available for use as a blocking control in assays to test for specificity of this CYP2A6 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CYP2A6

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Andere Bezeichnung: CYP2A6 (CYP2A6 Produkte)

Synonyme: CPA6 antikoerper, CYP2A antikoerper, CYP2A3 antikoerper, CYPIIA6 antikoerper, P450C2A antikoerper, P450PB antikoerper, cyp2a6 antikoerper, cytochrome P450 family 2 subfamily A member 6 antikoerper, cytochrome P450 2A6 antikoerper, cytochrome P450 family 2 subfamily A member 6 L homeolog antikoerper, CYP2A6 antikoerper, cyp2a6.L antikoerper

Hintergrund: CYP2A6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3, however, it has been renamed CYP2A6. Synonyms: Polyclonal CYP2A6 antibody, Anti-CYP2A6 antibody, cytochrome P450, family 2, subfamily A, polypeptide 6 antibody, CPA6 antibody, CYP2A antibody, CYP2A3 antibody, P450C2A antibody, P450PB antibody.