RNF115 Antikörper (AA 161-260) (Alexa Fluor 488)

Produktnummer ABIN920408

Produktdetails anti-RNF115 Antikörper (Alexa Fluor 488)

Target: RNF115 (Ring Finger Protein 115 (RNF115))

Bindungsspezifität: AA 161-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF115 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BCA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RNF115

Target: RNF115 (Ring Finger Protein 115 (RNF115))

Andere Bezeichnung: BCA2 (RNF115 Produkte)

Synonyme: BCA2 antikoerper, ZNF364 antikoerper, 2610028E05Rik antikoerper, AU042696 antikoerper, Zfp364 antikoerper, ring finger protein 115 antikoerper, RNF115 antikoerper, Rnf115 antikoerper

Hintergrund:

Synonyms: BCA2, Breast cancer associated gene 2, CL469780, Rabring 7, RING finger protein 115, RNF115, Zinc finger protein 364, RN115_HUMAN.

Background: The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.