TXN2 Antikörper (AA 101-166) (Alexa Fluor 488)

Produktnummer ABIN917567

Produktdetails anti-TXN2 Antikörper (Alexa Fluor 488)

Target: TXN2 (Thioredoxin 2 (TXN2))

Bindungsspezifität: AA 101-166

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXN2 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thioredoxin 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TXN2

Target: TXN2 (Thioredoxin 2 (TXN2))

Andere Bezeichnung: Thioredoxin 2 (TXN2 Produkte)

Synonyme: MT-TRX antikoerper, MTRX antikoerper, TRX2 antikoerper, 31884 antikoerper, CG31884 antikoerper, CG3864 antikoerper, DTrx-2 antikoerper, DmTrx-2 antikoerper, DmelTrx-2 antikoerper, Dmel\\CG31884 antikoerper, Trx antikoerper, anon-WO0118547.188 antikoerper, dmtrx-2 antikoerper, 2510006J11Rik antikoerper, AI788873 antikoerper, Trx2 antikoerper, zgc:77127 antikoerper, thioredoxin 2 antikoerper, thioredoxin-2 antikoerper, thiol reductase thioredoxin antikoerper, thioredoxin 2 L homeolog antikoerper, TXN2 antikoerper, Trx-2 antikoerper, LOC409451 antikoerper, VPA0972 antikoerper, VS_RS18125 antikoerper, VCD_000568 antikoerper, VEA_000083 antikoerper, trx2 antikoerper, Txn2 antikoerper, txn2 antikoerper, txn2.L antikoerper

Hintergrund:

Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

Gen-ID: 25828

Pathways: Cell RedoxHomeostasis