Pp1a/Pp2ca/Ppp1ca (AA 281-382) Antikörper (Alexa Fluor 350)

Produktnummer ABIN911758

Produktdetails

Target: Pp1a/Pp2ca/Ppp1ca

Bindungsspezifität: AA 281-382

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PPP1CA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Pp1a/Pp2ca/Ppp1ca

Hintergrund:

Synonyms: PP 1A, PP1A, PP2C ALPHA, PP2CA, PPP1CA, Protein Phosphatase 2C Alpha Isoform, Serine threonine protein phosphatase PP1 alpha catalytic subunit, EC 3.1.3.16, MGC15877, MGC1674, MGC9201.

Background: PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.

Gen-ID: 5499

UniProt: P62136