PMP22 Antikörper (AA 101-160) (Alexa Fluor 555)

Produktnummer ABIN911564

Produktdetails anti-PMP22 Antikörper (Alexa Fluor 555)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Bindungsspezifität: AA 101-160

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMP22 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PMP-22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Andere Bezeichnung: PMP22 (PMP22 Produkte)

Synonyme: CMT1A antikoerper, CMT1E antikoerper, DSS antikoerper, GAS-3 antikoerper, HMSNIA antikoerper, HNPP antikoerper, Sp110 antikoerper, 22kDa antikoerper, Gas-3 antikoerper, Tr antikoerper, trembler antikoerper, pmp22 antikoerper, wu:fa04d03 antikoerper, wu:fa08d03 antikoerper, MGC80653 antikoerper, PMP22 antikoerper, MGC69407 antikoerper, id:ibd2630 antikoerper, wu:fb81f09 antikoerper, zgc:136919 antikoerper, peripheral myelin protein 22 antikoerper, peripheral myelin protein 22a antikoerper, peripheral myelin protein 22 S homeolog antikoerper, peripheral myelin protein 22b antikoerper, PMP22 antikoerper, Pmp22 antikoerper, pmp22a antikoerper, pmp22.S antikoerper, pmp22 antikoerper, pmp22b antikoerper

Hintergrund:

Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3

Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

Gen-ID: 5376

UniProt: Q01453