PEA15 Antikörper (AA 51-130) (Alexa Fluor 488)

Produktnummer ABIN910627

Produktdetails anti-PEA15 Antikörper (Alexa Fluor 488)

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Bindungsspezifität: AA 51-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEA15 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEA15

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PEA15

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Andere Bezeichnung: PEA15 (PEA15 Produkte)

Synonyme: HMAT1 antikoerper, HUMMAT1H antikoerper, MAT1 antikoerper, MAT1H antikoerper, PEA-15 antikoerper, PED antikoerper, Pea15a antikoerper, PEA15 antikoerper, DKFZp459O1410 antikoerper, proliferation and apoptosis adaptor protein 15 antikoerper, phosphoprotein enriched in astrocytes 15 antikoerper, proliferation and apoptosis adaptor protein 15 L homeolog antikoerper, Astrocytic phosphoprotein PEA-15 antikoerper, PEA15 antikoerper, Pea15 antikoerper, pea15.L antikoerper, pea15 antikoerper

Hintergrund:

Synonyms: Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HUMMAT 1H, HUMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA-15_ PEA15 protein, PED, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes, PEA15_HUMAN.

Background: PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

Gen-ID: 8682