nectin-3 Antikörper (AA 431-549) (Alexa Fluor 647)

Produktnummer ABIN907893

Produktdetails anti-nectin-3 Antikörper (Alexa Fluor 647)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Bindungsspezifität: AA 431-549

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nectin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: Nectin 3 (NECTIN3 Produkte)

Synonyme: PVRL3 antikoerper, CD113 antikoerper, CDW113 antikoerper, NECTIN-3 antikoerper, PPR3 antikoerper, PRR3 antikoerper, PVRR3 antikoerper, 2610301B19Rik antikoerper, 3000002N23Rik antikoerper, 4921513D19Rik antikoerper, AA407785 antikoerper, AU016832 antikoerper, AW538082 antikoerper, nectin cell adhesion molecule 3 antikoerper, poliovirus receptor-related 3 antikoerper, Nectin3 antikoerper, NECTIN3 antikoerper, PVRL3 antikoerper, nectin3 antikoerper

Hintergrund:

Synonyms: CD113, CDw113, DKFZP566B0846, FLJ90624, Nectin-3, Nectin3, Poliovirus receptor related 3, Poliovirus receptor related protein 3, Poliovirus receptor-related protein 3, PPR3, PRR3, PVRL 3, PVRL3, PVRL3_HUMAN, PVRR3.

Background: Nectins are immunoglobulin-like adhesion molecules that interact with afadin. Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells.The nectin/PRR-family consists of four members, nectin-1, -2, -3 and -4. All the members of the nectin family have two or three slice variants. Nectin 3 is mainly expressed in testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.

Gen-ID: 25945

Pathways: Cell-Cell Junction Organization