PLEKHG6 Antikörper (AA 451-550) (HRP)

Produktnummer ABIN907488

Produktdetails anti-PLEKHG6 Antikörper (HRP)

Target: PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))

Bindungsspezifität: AA 451-550

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLEKHG6 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MyoGEF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PLEKHG6

Target: PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))

Andere Bezeichnung: MyoGEF (PLEKHG6 Produkte)

Synonyme: MyoGEF antikoerper, BC026778 antikoerper, Gm155 antikoerper, pleckstrin homology and RhoGEF domain containing G6 antikoerper, pleckstrin homology domain containing, family G (with RhoGef domain) member 6 antikoerper, PLEKHG6 antikoerper, Plekhg6 antikoerper

Hintergrund:

Synonyms: Myosin interacting guanine nucleotide exchange factor, PH domain containing family G member 6, Pleckstrin homology domain containing family G with RhoGef domain member 6, Pleckstrin homology domain-containing family G member 6, PLEKHG6_PKHG6_HUMAN

Background: MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Gen-ID: 55200