Kininogen-1 Heavy Chain (AA 281-356) Antikörper (Alexa Fluor 350)

Produktnummer ABIN905010

Produktdetails

Target: Kininogen-1 Heavy Chain

Bindungsspezifität: AA 281-356

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kininogen-1 heavy chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Kininogen-1 Heavy Chain

Synonyme: BDK antikoerper, BK antikoerper, KNG antikoerper, kininogen 1 antikoerper, KNG1 antikoerper

Hintergrund:

Synonyms: BDK, Kininogen 1, Kininogen1, Kininogen-1, KNG1, LMW, Low molecular weight growth promoting factor, Low molecular weight kininogen, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, HMWK heavy chain, Ile-Ser-Bradykinin, Kallidin I, Kallidin II, Kininogen 1, Kininogen 1 heavy chain, KNG, KNG1_HUMAN, Williams-Fitzgerald-Flaujeac factor.

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

Gen-ID: 3827