KCNQ1 Antikörper (AA 501-600) (Alexa Fluor 350)

Produktnummer ABIN903537

Produktdetails anti-KCNQ1 Antikörper (Alexa Fluor 350)

Target: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Bindungsspezifität: AA 501-600

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNQ-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNQ1

Target: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Andere Bezeichnung: KCNQ1 (KCNQ1 Produkte)

Synonyme: ATFB1 antikoerper, ATFB3 antikoerper, JLNS1 antikoerper, KCNA8 antikoerper, KCNA9 antikoerper, KVLQT1 antikoerper, Kv1.9 antikoerper, Kv7.1 antikoerper, LQT antikoerper, LQT1 antikoerper, RWS antikoerper, SQT2 antikoerper, WRS antikoerper, CG12215 antikoerper, CG12915 antikoerper, CG33135 antikoerper, DKCNQ antikoerper, Dmel\\CG33135 antikoerper, dKCNQ antikoerper, kcnq1 antikoerper, KCNQ1 antikoerper, kqt-3 antikoerper, kv7.1 antikoerper, Kvlqt1 antikoerper, KvLQT-1 antikoerper, kcnq1-A antikoerper, xkvlqt1 antikoerper, zgc:158384 antikoerper, AW559127 antikoerper, Kcna9 antikoerper, KvLQT1 antikoerper, potassium voltage-gated channel subfamily Q member 1 antikoerper, KCNQ potassium channel antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 1 antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 1 antikoerper, voltage gated potassium channel subunit antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antikoerper, potassium voltage-gated channel, subfamily Q, member 1 antikoerper, KCNQ1 antikoerper, KCNQ antikoerper, kcnq1 antikoerper, Kcnq1 antikoerper, kcnq1.L antikoerper

Hintergrund:

Synonyms: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv7.1, KCNQ1

Background: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.

Gen-ID: 3784

UniProt: P51787

Pathways: Negative Regulation of Hormone Secretion, Sensory Perception of Sound